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Knowledge Base

Solvent First Protein Precipitation

TELOS® PPT Protein Precipitation Plates and Columns are designed for the clean-up of biological fluid samples, particularly plasma.  Available in both 1ml columns and 96-well plates, the product is ideally suited to both high through sample preparation and variable and small sample numbers.

Efficient and Reliable Protein Precipitation The double fritted design includes proprietary and large porosity frits for rapid and trouble-free protein precipitation.  The proprietary frit holds up the precipitation solvent, acetonitrile, creating a “pool” for the plasma to be dispended into.  The larger porosity frit prevents blocking, allowing reproducible collection of the subsequent filtrate.

No Filtrate Breakthrough Extensive testing of the TELOS PPT Product guarantees no acetonitrile or acetonitrile/plasma mixture breakthrough during the process.  Only when the subsequent vacuum is applied, will the filtrate pass into the collection vial or plate.

No Offline Steps TELOS PPT Columns and Plates remove the need for tedious off line liquid handling and centrifugation steps.  The entire process occurs in situ.

96-well and 1ml Column Formats TELOS PPT Protein Precipitation Products are available in both 96-well plates and 1ml columns.  The 96-well plate is optimised for high throughput methods that require the microtitre plate format.  For methods and applications that require single columns, or have small and varying sample numbers, using the 1ml column. 

Order online or call 01480 212122 for more information