Knowledge Base
CHIRALPAK immobilised phases
CHIRALPAK IA, IB, IC, ID, IE, IF and IG HPLC columns are a newer generation of chiral stationary phases (CSPs), in which the polysaccharide chiral selector has been chemically immobilised on to a wide pore silica matrix. This process confers enhanced robustness and stability to these columns.
These innovative immobilised CSPs allow chromatographers to use essentially any organic solvent as mobile phases to develop the most challenging chiral separations. This is in contrast to traditional, coated polysaccharide phases which have restricted solvent compatibility. The broader range of solvents that can be used introduces new selectivity profiles and improved productivity compared with traditional coated polysaccharide phases.
CHIRALPAK material specifications
CHIRALPAK phase | Chiral selector | |
CHIRALPAK IA | Amylose tris (3, 5-dimethylphenylcarbamate) | Browse Columns |
CHIRALPAK IB | Cellulose tris (3, 5-dimethylphenylcarbamate) | Browse Columns |
CHIRALPAK IC | Cellulose tris (3, 5-dichlorophenylcarbamate) | Browse Columns |
CHIRALPAK ID | Amylose tris (3-chlorophenylcarbamate) | Browse Columns |
CHIRALPAK IE | Amylose tris (3, 5-dichlorophenylcarbamate) | Browse Columns |
CHIRALPAK IF | Amylose tris (3-chloro, 4-methylphenylcarbamate) | Browse Columns |
CHIRALPAK IG | Amylose tris- (3-chloro-5-methylphenylcarbamate) | Browse Columns |
Columns with particle sizes of 5um (CHIRALPAK IA, IB, IC, ID, IE, IF and IG) and 3um (CHIRALPAK IA-3, IB-3, IC-3, ID-3, IE-3, IF-3 and IG-3) are available. Methods can be transferred directly from 5um to 3um particle size columns for faster separations. Immobilised phases can be used in all chromatographic modes: normal- and reversed-phase HPLC, SFC, analytical and preparative.
Column screening is simpler, faster and more successful using Daicel immobilised phases. Using the three immobilised phases IA, IC and IG offers a baseline separation success rate of 84%.
Special Offer
Don't miss our Daicel Immobilised Chiral Columns Special Offer, on now until October 31st 2017. Click here for details »
Further Information
Click a thumbnail below to download the CHIRALPAK IG leaflet, the iChiral-6 Brochure or the full Daicel Chiral Columns Catalogue.